Product Name: R406
Subtitle: SYK inhibitor,potent and ATP-competitive
Biological Activity: Biological Activity of R406Description R406 is a potent inhibitor of Syk with IC50 of 41 nM. Targets Syk IC50 41 nM
SMLES: CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)O
CAS NO: 164650-44-6
Standard In CHIKey: TSH Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H23FN6O5.C6H6O3S
M.Wt: 628.63
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/3/1573
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: benzenesulfonic acid;6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one