Product Name: RN 1747
Subtitle:
Biological Activity: Biological Activity of RN 1747Selective TRPV4 agonist (EC50 values are 0.77, 4.0 and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively). Displays selectivity over other TRP channels (EC50 values are 0.77, >30, >30 and >100 μM for TRPV4,
SMLES: ClC1=CC=C(C([N+]([O-])=O)=C1)S(=O)(N2CCN(CC3=CC=CC=C3)CC2)=O
CAS NO: 111011-76-8
Standard In CHIKey: TNF-alpha inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H18ClN3O4S
M.Wt: 395.87
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/2/718
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine