Product Name: Ro 19-4603
Subtitle:
Biological Activity: Biological Activity of Ro 19-4603Benzodiazepine inverse agonist. Binds with high affinity to both diazepam-sensitive (DS) and diazepam-insensitive (DI) GABAA receptors (Ki values are ~ 0.2 and ~ 2.6 nM for DS and DI receptors respectively). Antagonizes ef
SMLES: O=C1N(C)CC2=C(C(OC(C)(C)C)=O)N=CN2C3=C1SC=C3
CAS NO: 72873-74-6
Standard In CHIKey: ZIGMMUKDYCABPW-UHFFFAOYSA-NDYRK inhibitors
Standard InChI: InChI=1S/C15H17N3O3S/c1-15(2,3)21-14(20)11-10-7-17(4)13(19)12-9(5-6-22-12)18(10)8-16-11/h5-6,8H,7H2,1-4H3
Typrof Compound:
Appearance:
Formula: C15H17N3O3S
M.Wt: 319.38
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/273/3/1428
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in ethanol and to 100 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester