Product Name: Rostafuroxin (PST 2238)
Subtitle: Selective antagonist of endogenous ouabain, antihypertensive agent
Biological Activity: Biological Activity of Rostafuroxin (PST 2238)Na+/K+ ATPase modulator. Normalizes renal Na+/K+ ATPase pump function in mutant adducin- and endogenous ouabain-dependent forms of hypertension. Reduces blood pressure in Milan hypersensitive rats. Controls ma
SMLES: C[C@]12CC[C@@](O)([H])C[C@@]1([H])CC[C@]3([H])[C@]2([H])CC[C@@]4([C@](C5=COC=C5)(O)CC[C@]34O)C
CAS NO: 349554-02-5
Standard In CHIKey: AEAPORIZZWBIEX-DTBDINHYSA-NGPCR19 inhibitors
Standard InChI: InChI=1S/C23H34O4/c1-20-8-5-17(24)13-15(20)3-4-19-18(20)6-9-21(2)22(25,10-11-23(19,21)26)16-7-12-27-14-16/h7,12,14-15,17-19,24-26H,3-6,8-11,13H2,1-2H3/t15-,17+,18+,19-,20+,21-,22+,23+/m1/s1
Typrof Compound:
Appearance:
Formula: C23H34O4
M.Wt: 374.51
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/272/3/1313
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: 3β,5β,14β)-21,23-Epoxy-24-norchola-20,22-diene-3,14,17-triol