Product Name: Ryuvidine
Subtitle:
Biological Activity: Biological Activity of RyuvidineInhibitor of SETD8 protein lysine methyltransferase (PKMT) (IC50 = 0.5 μM); suppresses H4K20 monomethylation in vitro. Also inhibits cyclin-dependent kinase (CDK) 4 (IC50 = 6.0 μM at CDK4/cyclin D1). Induces S phase
SMLES: O=C(C1=C2SC(C)=N1)C(NC3=CC=C(C)C=C3)=CC2=O
CAS NO: 1629125-65-0
Standard In CHIKey: CCR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C15H12N2O2S
M.Wt: 284.33
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/260/2/780
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 20 mM in DMSO and to 5 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: 2-Methyl-5-[(4-methylphenyl)amino]-4,7-benzothiazoledione