Product Name: SAR245409 (XL765)
Subtitle: mTOR/PI3K inhibitor
Biological Activity: Biological Activity of SAR245409 (XL765)Description SAR245409 (XL765) is a dual inhibitor of mTOR/PI3K. Targets PI3Kγ PI3Kα PI3Kδ PI3Kβ DNA-PK mTOR IC50 9 nM 39 nM 43 nM 113 nM 150 nM 157 nM
SMLES: CC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC
CAS NO: 195514-63-7
Standard In CHIKey: p97 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C31H29N5O6S
M.Wt: 599.66
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/681
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: N-[4-[[3-(3,5-dimethoxyanilino)quinoxalin-2-yl]sulfamoyl]phenyl]-3-methoxy-4-methylbenzamide