Product Name: SB 706375
Subtitle:
Biological Activity: Biological Activity of SB 706375High affinity, non-peptide antagonist of the urotensin-II (UT) receptor. Exhibits high affinity for mammalian UT receptors, including human, mouse and rat (Ki values are 9.3, 19.1 and 20.7 nM respectively, in HEK293 cells e
SMLES: BrC(C=C1OC)=C(C=C1OC)S(=O)(NC2=CC=C(C(F)(F)F)C(O[C@@H]3CCN(C)C3)=C2)=O
CAS NO: 298690-60-5
Standard In CHIKey: APC inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H22BrF3N2O5S
M.Wt: 539.36
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/264/2/530
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 2-Bromo-4,5-dimethoxy-N-[3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]-4-(trifluoromethyl)phenyl]benzenesulfonamide