Product Name: SCH 51344
Subtitle: MTH1 inhibitor
Biological Activity: Biological Activity of SCH 51344Potent MTH1 inhibitor (Kd = 49 nM). Inhibits Ras-induced malignant transformation and increases α-actin promoter-driven CAT activity in Ras-transformed cells. Has no effect on Ras-induced ERK and JNK activation. Inhibi
SMLES: CC1=NN=C(N2)C1=C(NCCOCCO)C3=C2C=CC(OC)=C3
CAS NO: 849479-74-9
Standard In CHIKey: MAPKAPK2 MK2) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C16H20N4O3
M.Wt: 316.35
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/260/3/1314
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: 2-[2-[(6-Methoxy-3-methyl-1H-pyrazolo[3,4-b]quinolin-4-yl)amino]ethoxy]ethanol