Product Name: SDZ 220-581
Subtitle: NMDA glutamate receptor subtype antagonist
Biological Activity: Biological Activity of SDZ 220-581Competitive NMDA receptor antagonist (pKi = 7.7). Centrally active following oral administration (ED50 < 3.2 mg/kg for protection against MES-induced seizures).
SMLES: C1=CC=C(C(=C1)C2=CC(=CC(=C2)CP(=O)(O)O)CC(C(=O)O)N)Cl
CAS NO: 1448671-31-5
Standard In CHIKey: VBRJFXSFCYEZMQ-HNNXBMFYSA-NDopamine Receptor inhibitors
Standard InChI: InChI=1S/C16H17ClNO5P/c17-14-4-2-1-3-13(14)12-6-10(8-15(18)16(19)20)5-11(7-12)9-24(21,22)23/h1-7,15H,8-9,18H2,(H,19,20)(H2,21,22,23)/t15-/m0/s1
Typrof Compound:
Appearance:
Formula: C16H17ClNO5P
M.Wt: 369.74
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/258/3/753
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in DMSO with gentle warming and to 100 mM in 1.1eq. NaOH
Storage: Store at RT
Purity: >98%
Chemical Name: (S)-α-Amino-2-chloro-5-(phosphonomethyl)[1,1-biphenyl]-3-propanoic acid