Product Name: SIB 1757
Subtitle:
Biological Activity: Biological Activity of SIB 1757A highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype; displays an IC50 value of 0.4 μM at hmGlu5 compared with > 30 μM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8.
SMLES: O=C1/C(N=C(C)C=C1)=N/NC2=CC=CC=C2
CAS NO: 13636-18-5
Standard In CHIKey: GPCR19 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C12H11N3O
M.Wt: 213.24
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/270/1/26
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 6-Methyl-2-(phenylazo)-3-pyridinol