Product Name: TCS 359
Subtitle: Potent FLT3 inhibitor
Biological Activity: Biological Activity of TCS 359Potent inhibitor of FLT3 receptor tyrosine kinase (IC50 = 42 nM) that displays selectivity over a range of other kinases. Exhibits antiproliferative effects on MV4-11 cells, a human acute myelogenous leukemia cell line expres
SMLES: COc1ccc(cc1OC)C(=O)Nc2c(c3c(s2)CCCC3)C(=O)N
CAS NO: 1396257-94-5
Standard In CHIKey: MAPK_ERK Pathway inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C18H20N2O4S
M.Wt: 360.43
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/1/248
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 30 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide