Product Name: TSU-68 (SU6668,Orantinib)
Subtitle: PDGFR/Flk-1/FGFR1 inhibitor,potent and competitive
Biological Activity: Biological Activity of TSU-68 (SU6668,Orantinib)ATP-competitive PDGFR, VEGF and FGFR inhibitor (IC50 values are 0.06, 2.43, 3.04 and > 100 μM at PDGFRβ, VEGFR2, FGFR1 and EGFR respectively). Inhibits proliferation of HUVEC and NIH3T3 cells in
SMLES: CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=CC=CC=C3NC2=O
CAS NO: 596-09-8
Standard In CHIKey: NHFDRBXTEDBWCZ-NTEUORMPSA-NCRTH2 GPR44) inhibitors
Standard InChI: InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9+
Typrof Compound:
Appearance:
Formula: C18H18N2O3
M.Wt: 310.35
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/3/1278
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 5-[1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid