Product Name: Telatinib (BAY 57-9352)
Subtitle: VEGFR-2/-3,PDGFR-β and c-Kit inhibitor
Biological Activity: Biological Activity of Telatinib (BAY 57-9352)Description Telatinib is a potent inhibitor of VEGFR2/3, c-Kit and PDGFRβ with IC50 values of 6 nM/4 nM, 1 nM and 15 nM, respectively. Targets c-Kit VEGFR3 VEGFR2 PDGFRα IC50 1 nM 4 nM 6
SMLES: CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl
CAS NO: 1094873-14-9
Standard In CHIKey: Urotensin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H16ClN5O3
M.Wt: 409.83
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/1/1
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-[[4-(4-chloroanilino)furo[2,3-d]pyridazin-7-yl]oxymethyl]-N-methylpyridine-2-carboxamide