Product Name: Tenovin-6
Subtitle: SIRT inhibitor and p53 activator
Biological Activity: Biological Activity of Tenovin-6Description Tenovin-6 is an inhibitor of sirtuin with IC50 values of 21 µM, 10 µM and 67 µM for SIRT1, SIRT2 and SIRT3, respectively. Targets SIRT1 SIRT2 SIRT3 p53 IC50 21 µM 10 µM 67 µM
SMLES: CC(C)(C)C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC=C(C=C2)NC(=O)CCCCN(C)C
CAS NO: 195055-03-9
Standard In CHIKey: Itk inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H34N4O2S
M.Wt: 454.6
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/1008
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-tert-butyl-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide