Product Name: Vandetanib (ZD6474)
Subtitle: VEGFR2/EGFR antagonist
Biological Activity: Biological Activity of Vandetanib (ZD6474)Description Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with an IC50 value of 40 nM. Targets VEGFR2 IC50 40 nM
SMLES: CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC
CAS NO: 315183-21-2
Standard In CHIKey: UHTHHESEBZOYNR-UHFFFAOYSA-NVasopressin Receptor inhibitors
Standard InChI: InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)
Typrof Compound:
Appearance:
Formula: C22H24BrFN4O2
M.Wt: 475.35
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/1/101
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Limited solubility
Storage:
Purity: >98%
Chemical Name: N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine