Product Name: WDR5 0103
Subtitle: WD repeat-containing protein 5 (WDR5) antagonist
Biological Activity: Biological Activity of WDR5 0103WD repeat-containing protein 5 (WDR5) antagonist (Kd = 450 nM). Disrupts WDR5 interaction with MLL and inhibits MLL core complex methyltransferase activity in vitro. Has no effect on a panel of seven other methyltransferase
SMLES: COC(C1=CC(NC(C2=CC=CC(OC)=C2)=O)=C(N3CCN(C)CC3)C=C1)=O
CAS NO: 555-66-8
Standard In CHIKey: Metabolism/Protease_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H25N3O4
M.Wt: 383.44
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/951
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: 3-[(3-Methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)benzoic acid methyl ester