Product Name: WYE-125132 (WYE-132)
Subtitle: ATP-competitive mTOR inhibitor, highly potent
Biological Activity: Biological Activity of WYE-125132 (WYE-132)Description WYE-125132 (WYE-132) is a highly potent, ATP-competitive inhibitor of mTOR with an IC50 value of 0.19 nM. Targets mTOR IC50 0.19 nM
SMLES: CNC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCC5(CC4)OCCO5)C(=N2)N6CC7CCC(C6)O7
CAS NO: 1811-28-5
Standard In CHIKey: Neurotensin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C27H33N7O4
M.Wt: 519.61
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/271/1/200
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 1-[4-[1-(1,4-dioxaspiro[4.5]decan-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-3-methylurea