Product Name: WZ4003
Subtitle: NUAK1/2 inhibitor, potent and selective
Biological Activity: Biological Activity of WZ4003Potent and selective NUAK1/2 inhibitor (IC50 values are 20 and 100 nM respectively). Exhibits no significant inhibition against a panel of 139 kinases, including ten AMPK family members. Inhibits NUAK1-mediated MYPT1 phosphory
SMLES: CCC(=O)NC1=CC(=CC=C1)OC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC
CAS NO: 17780-75-5
Standard In CHIKey: Histamine Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H29ClN6O3
M.Wt: 496.99
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/271/1/14
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in 1eq. HCl and to 20 mM in DMSO with gentle warming
Storage: Store at -20℃
Purity: >98%
Chemical Name: N-3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]propanamide