Product Name: ZD 7288
Subtitle: HCN channel inhibitor
Biological Activity: Biological Activity of ZD 7288Sino-atrial node function modulator; blocks the hyperpolarization activated cation current If (HCN channel). Blocks Ih in central neurons. Increases NMDA-evoked noradrenalin release in rat brain in vitro.
SMLES: CCN(C1=CC=CC=C1)C2=C/C(N(C)C(C)=N2)=NC.Cl
CAS NO: 912287-56-0
Standard In CHIKey: DUWKUHWHTPRMAP-UHFFFAOYSA-N5 alpha Reductase inhibitors
Standard InChI: InChI=1S/C15H20N4.ClH/c1-5-19(13-9-7-6-8-10-13)15-11-14(16-3)18(4)12(2)17-15;/h6-11H,5H2,1-4H3;1H
Typrof Compound:
Appearance:
Formula: C15H21ClN4
M.Wt: 292.81
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/273/2/656
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: 4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride