Product Name: ZM 449829
Subtitle: JAK3 inhibitor
Biological Activity: Biological Activity of ZM 449829Potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3) which binds competitively to the JAK3 ATP site. pIC50 values are 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively. Inhibits STAT-5 phosphor
SMLES: O=C(C=C)C1=CC2=C(C=C1)C=CC=C2
CAS NO: 1956370-21-0
Standard In CHIKey: Serotonin Transporter inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C13H10O
M.Wt: 182.22
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/2/580
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility:
Storage: Desiccate at -20℃
Purity: >98%
Chemical Name: 1-(2-Naphthalenyl)-2-propen-1-one