Mouse DLK1 Protein 3984

Additional Information:
accession Q09163|express systemHEK293|product tagC-His|purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC|backgroundpaternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome.|molecular weightThe protein has a predicted MW of 30.9 kDa. Due to glycosylation, the protein migrates to 50-68 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|Mouse DLK1 Protein 3984proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevancepaternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome.Protein namesProtein delta homolog 1 (DLK-1) (Adipocyte differentiation inhibitor protein) (Preadipocyte factor 1) (Pref-1) [Cleaved into: Fetal antigen 1 (FA1)]Gene namesDlk1,Dlk1 Dlk Pref1 Scp-1Mass10090DaFunctionMay have a role in neuroendocrine differentiation. Inhibits adipocyte differentiation.Subellular locationMembrane; Single-pass type I membrane protein. Cytoplasm .TissuesHighly expressed in fetal liver, placenta, adult adrenal gland, brain, testis and ovary and, to a lesser degree, in adult kidney, muscle, thymus and heart.StructureMonomer. Interacts with SH3RF2 (By similarity).Post-translational modificationN- and O-glycosylated.Target Relevance information above includes information from UniProt accession: Q09163The UniProt Consortium|