**Background**
Dipeptides are the simplest form of peptides, consisting of two amino acids linked by a peptide bond. They serve as critical building blocks in protein synthesis and play diverse roles in cellular signaling, metabolic regulation, and structural stability. Among these, the interaction between basic and acidic amino acids is of particular interest in structural biology. Specifically, the guanidyl-carboxylate interaction between arginine and aspartic acid provides essential insights into how proteins fold and how molecular recognition occurs within biological systems. Understanding these fundamental interactions is crucial for the development of peptide-based therapeutics and the study of protein-protein interactions. In this context, we will introduce a dipeptide composed of arginine and aspartic acid – Arginylaspartic acid.
**Definition**
Arginylaspartic acid is a dipeptide consisting of the amino acids arginine and aspartic acid, often provided as an acetate salt. According to the Arginylaspartic acid description, it is characterized by the sequence Arg-Asp (RD).
**Chemical Properties and Structural Analysis**
The Arginylaspartic acid Formula is $\text{C}_{12}\text{H}_{23}\text{N}_5\text{O}_7$, with a molecular weight of 349.34. From a structural perspective, this dipeptide is utilized to study the specific spatial arrangements and electrostatic interactions between the guanidinium group of arginine and the carboxylate group of aspartic acid. Research focusing on Arginylaspartic acid biological activity has utilized crystal structures to demonstrate how these two residues interact to form stable salt bridges, which are pivotal for the stability of many tertiary protein structures. For researchers requiring high-quality reagents, verifying the Arginylaspartic acid purity & documentation is essential to ensure the accuracy of structural and biochemical assays. In conclusion, Arginylaspartic acid is a valuable dipeptide tool for studying guanidyl-carboxylate interactions and peptide chemistry.
Keywords
Arginylaspartic acid, 496949-01-0, Others, Inhibitor, inhibitor, inhibit
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