Product Name: 5-Azacytidine
Subtitle: DNA methyltransferase inhibitor.
Biological Activity: Biological Activity of 5-AzacytidineDNA methyltransferase inhibitor. Incorporates into DNA forming covalent adducts with cellular DNMT1, depleting enzyme activity. Induces demethylation and reactivation of silenced genes. Improves the efficiency of reprog
SMLES:
CAS NO: 173897-44-4
Standard In CHIKey: NMUSYJAQQFHJEW-KVTDHHQDSA-NHistone Demethylase inhibitors
Standard InChI: InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1
Typrof Compound:
Appearance:
Formula: C8H12N4O5
M.Wt: 244.2
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/508
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in water and to 100 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one