hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit

Product Name : hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunitTarget gene : HADHBverified_species_reactivity : Humaninterspecies_information : 96%, ENSMUSG00000059447, species_id: MOUSE, 96%, ENSRNOG00000010800, species_id: RATclonality : Polyclonalisotype : IgGhost :…

Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma and Myoepithelial Cell Marker) Recombinant Rabbit Monoclonal Antibody (MYH11/8185R)

Product Name : Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma and Myoepithelial Cell Marker) Recombinant Rabbit Monoclonal Antibody (MYH11/8185R)Species Reactivity: HumanHost/Isotype : Rabbit / IgG, kappaClass:Recombinant MonoclonalType : AntibodyClone: MYH11/8185RConjugate…

SBI-0640756

Product Name : SBI-0640756Description:SBI-0640756 (SBI-756) is an inhibitor of eIF4G1 and disrupts the eIF4F complex.CAS: 1821280-29-8Molecular Weight:404.82Formula: C23H14ClFN2O2Chemical Name: 6-chloro-3--4-phenyl-1,2-dihydroquinolin-2-oneSmiles : O=C1NC2C=CC(Cl)=CC=2C(=C1C(=O)/C=C/C1C=NC=C(F)C=1)C1C=CC=CC=1InChiKey: VVWGPQZBDQVQRC-RMKNXTFCSA-NInChi : InChI=1S/C23H14ClFN2O2/c24-16-7-8-19-18(11-16)21(15-4-2-1-3-5-15)22(23(29)27-19)20(28)9-6-14-10-17(25)13-26-12-14/h1-13H,(H,27,29)/b9-6+Purity: ≥98% (or refer to the…

Pavinetant

Product Name : PavinetantDescription:Pavinetant (MLE-4901) is a neurokinin-3 receptor (NK3R) antagonist.CAS: 941690-55-7Molecular Weight:459.56Formula: C26H25N3O3SChemical Name: 3-methanesulfonamido-2-phenyl-N-quinoline-4-carboxamideSmiles : CS(=O)(=O)NC1C(=C2C=CC=CC2=NC=1C1=CC=CC=C1)C(=O)N(CC)C1=CC=CC=C1InChiKey: QYTBBBAHNIWFOD-NRFANRHFSA-NInChi : InChI=1S/C26H25N3O3S/c1-3-21(18-12-6-4-7-13-18)28-26(30)23-20-16-10-11-17-22(20)27-24(19-14-8-5-9-15-19)25(23)29-33(2,31)32/h4-17,21,29H,3H2,1-2H3,(H,28,30)/t21-/m0/s1Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition:…

Cyclic-di-GMP

Product Name : Cyclic-di-GMPDescription:Cyclic-di-GMP (c-di-GMP) is a STING activator and a ubiquitous second messenger that regulates biofilm formation, motility, and virulence in diverse bacterial species.CAS: 61093-23-0Molecular Weight:690.41Formula: C20H24N10O14P2Chemical Name: (1S,6R,8R,9R,10S,15R,17R,18R)-8,17-bis(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,9,12,18-tetrahydroxy-2,4,7,11,13,16-hexaoxa-3λ⁵,12λ⁵-diphosphatricyclooctadecane-3,12-dioneSmiles…

Presatovir

Product Name : PresatovirDescription:Presatovir (GS-5806) is an orally bioavailable RSV fusion inhibitor with a mean EC50 value of 0.43 nM.CAS: 1353625-73-6Molecular Weight:532.06Formula: C24H30ClN7O3SChemical Name: N-2--6-methylpyrazolopyrimidin-2-ylpiperidine-1-carbonyl]-4-chlorophenylmethanesulfonamideSmiles : CC1=CN2N=C(C=C2N=C1N1C(N)CC1)1CCCCN1C(=O)C1=CC(Cl)=CC=C1NS(C)(=O)=OInChiKey: GOFXWTVKPWJNGD-UWJYYQICSA-NInChi : InChI=1S/C24H30ClN7O3S/c1-15-13-32-22(27-23(15)30-10-8-17(26)14-30)12-20(28-32)21-5-3-4-9-31(21)24(33)18-11-16(25)6-7-19(18)29-36(2,34)35/h6-7,11-13,17,21,29H,3-5,8-10,14,26H2,1-2H3/t17-,21-/m0/s1Purity:…

GSK205

Product Name : GSK205Description:GSK205 is a potent, selective TRPV4 antagonist with an IC50 of 4.19 μM for inhibiting TRPV4-mediated Ca2+ influx.CAS: 1263068-83-2Molecular Weight:481.45Formula: C24H25BrN4SChemical Name: N-(4-2-ethylphenyl)-5-(pyridin-3-yl)-1,3-thiazol-2-amine hydrobromideSmiles : Br.CN(CC1C=CC=CC=1)CCC1C=CC(=CC=1)NC1=NC=C(S1)C1C=NC=CC=1InChiKey: LQGOJHGNGSOUKL-UHFFFAOYSA-NInChi…

GNF-PF-3777

Product Name : GNF-PF-3777Description:GNF-PF-3777 (8-Nitrotryptanthrin) is a potent human indoleamine 2,3-dioxygenase 2 (hIDO2) inhibitor which significantly reduces IDO2 activity with Ki of 0.97 μM.CAS: 77603-42-0Molecular Weight:293.23Formula: C15H7N3O4Chemical Name: 8-nitro-6H,12H-indoloquinazoline-6,12-dioneSmiles :…

Dimenhydrinate

Product Name : DimenhydrinateDescription:Dimenhydrinate is an anti-emetic and anti-histamine commonly available over-the-counter as a motion sickness remedy.CAS: 523-87-5Molecular Weight:469.96Formula: C24H28ClN5O3Chemical Name: 8-chloro-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione; dimethylamineSmiles : CN(C)CCOC(C1C=CC=CC=1)C1C=CC=CC=1.CN1C(=O)C2NC(Cl)=NC=2N(C)C1=OInChiKey: NFLLKCVHYJRNRH-UHFFFAOYSA-NInChi : InChI=1S/C17H21NO.C7H7ClN4O2/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h3-12,17H,13-14H2,1-2H3;1-2H3,(H,9,10)Purity: ≥98% (or…

Lycoramine hydrobromide

Product Name : Lycoramine hydrobromideDescription:Lycoramine hydrobromide, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine hydrobromide is a potent acetylcholinesterase (AChE) inhibitor.CAS: 89505-76-0Molecular Weight:370.28Formula: C17H24BrNO3Chemical Name: (1R,12S,14S)-9-methoxy-4-methyl-11-oxa-4-azatetracycloheptadeca-6,8,10(17)-trien-14-ol hydrobromideSmiles :…

AA26-9

Product Name : AA26-9Description:AA26-9 is a potent and broad spectrum inhibitor of Serine hydrolases (SHs).CAS: 1312782-34-5Molecular Weight:166.18Formula: C7H10N4OChemical Name: 1-(pyrrolidine-1-carbonyl)-1H-1,2,3-triazoleSmiles : O=C(N1C=CN=N1)N1CCCC1InChiKey: IFXGAMVQLDJRBQ-UHFFFAOYSA-NInChi : InChI=1S/C7H10N4O/c12-7(10-4-1-2-5-10)11-6-3-8-9-11/h3,6H,1-2,4-5H2Purity: ≥98% (or refer to the…

3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B

Product Name : 3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin BDescription:3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B is a chemical constituent of the plant Poria cocos .CAS: 1260252-18-3Molecular Weight:780.94Formula: C41H64O14Chemical Name: (1S,3R,6R,7S,8S,9S,10S,11S,14S,16S)-6-acetyl-8-(acetyloxy)-10,16-dihydrogenio-14-oxy-4-methoxy-6-methyloxan-2-yl]oxy-7,11-dimethyl-2-oxapentacyclooctadecan-9-yl 2-methylpropanoateSmiles : CC(C)C(=O)O123(CC4C(CC42C)O2C(OC)(O4O(C)(O)(OC)4O)(C)O2)O23CC(C(C)=O)2(C)1OC(C)=OInChiKey: DAXMBTMYJCYTRG-IRCPNMLKSA-NInChi : InChI=1S/C41H64O14/c1-19(2)36(46)53-33-34-38(7)14-12-25(52-28-18-27(47-9)31(22(5)49-28)54-37-30(45)32(48-10)29(44)21(4)50-37)17-24(38)11-15-40(34)41(55-40)16-13-26(20(3)42)39(41,8)35(33)51-23(6)43/h19,21-22,24-35,37,44-45H,11-18H2,1-10H3/t21-,22-,24+,25+,26+,27-,28+,29-,30-,31-,32-,33+,34-,35-,37+,38+,39+,40+,41-/m1/s1Purity: ≥98% (or refer…

Doxycycline Hydrochloride

Product Name : Doxycycline HydrochlorideDescription:Doxycycline Hydrochloride is a broad-spectrum antibiotic, functioning as an inhibitor of matrix metalloproteinases.CAS: 10592-13-9Molecular Weight:480.90Formula: C22H25ClN2O8Chemical Name: (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochlorideSmiles : Cl.C12(O)3(C(O)=C(C(N)=O)C(=O)3(O)C(O)=C2C(=O)C2=C1C=CC=C2O)N(C)CInChiKey: RUYHIJHUVHIMIR-CVHRZJFOSA-NInChi : InChI=1S/C22H24N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);1H/t7-,10+,14+,15-,17-,22-;/m0.Fluvoxamine In Vitro…

0,4 0,four two,3 two,2 0,two 0,1 0,9 1,1 16,five 17,3 1,1 1,1 43,five 42,0 0,0 0,0 0,4 0,five 0,5 0,5 0,0 0,0 0,0 0,0 Obese 1,eight 1,4 0,9 0,7 0,0 0,1 1,1 1,1 0,1 0,1 1,0 1,0 0,0 0,0 0,1 0,9 1,4 1,9 0,two 0,1 4,0 five,7 0,0 0,0 0,1 0,2 0,1 0,three 0,0 0,0 0,0 0,0 Obese 0,0 0,0 0,three 0,1 0,two 0,0 31,five two,6 0,1 0,0 0,5 0,1 0,four 0,1 14,0 2,1 7,9 0,7b 1,three 0,2 16,three 2,7 0,1 0,0 0,0 0,0 0,2 0,1 0,2 0,0 0,four 0,1 4,1 0,6b 12,5 2,1 1,0 0,4 0,4 0,1 0,three 0,1 1,0 0,2 4,eight 0,9 -Absolute concentrations (M) Standard weight Overweight 23,1 15,0 17,7 eight,5 2,0 0,7 103,9 20,7 four,0 0,9 21,1 ten,3 1,3 0,two 8,1 0,7 147,6 24,6 10,three two,6 386,7 52,4 0,0 0,0 3,9 1,3 4,three 1,2 0,0 0,0 0,0 0,12:0 14:0 15:0 16:0 16:1 n-

0,four 0,four two,3 two,two 0,2 0,1 0,9 1,1 16,five 17,three 1,1 1,1 43,5 42,0 0,0 0,0 0,4 0,five 0,5 0,five 0,0 0,0 0,0 0,0 Obese 1,8 1,four 0,9 0,7 0,0…

Diagnosis with acceptable antimicrobial therapy saves each sight and life. This

Diagnosis with acceptable antimicrobial therapy saves both sight and life. This study documents circumstances of mucormycosis and their managementfromauniqueperspective. Mostofthestudiesdoneonmucormycosisareretrospective. Duetoincreaseinnumberofcases,diverseriskfactors,and inclusion of immunocompetent and immunocompromised sufferers, this study was…