Product Name: ARRY 520 trifluoroacetate
Subtitle: KSP inhibitor
Biological Activity: Biological Activity of ARRY 520 trifluoroacetatePotent kinesin spindle protein (KSP) inhibitor (IC50 = 6 nM); selective for KSP over >250 other receptors and kinases at a concentration of 10 μM. Displays robust antitumor activity in bortezomib-r
SMLES:
CAS NO: 1051375-16-6
Standard In CHIKey: Factor Xa inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H22F2N4O2S.CF3CO2H
M.Wt: 420.48
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/225
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 75 mM in DMSO and to 75 mM in ethanol
Storage: Store at -20℃
Purity: >98%
Chemical Name: (2S)-2-(3-Aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide trifluoroacetate