Product Name: AZ20
Subtitle: ATR inhibitor,potent and selective
Biological Activity: Biological Activity of AZ20Potent and selective ATR kinase inhibitor (IC50 = 5 nM). Exhibits 7.6-fold selectivity over mTOR and selectivity over a panel of 442 kinases, including ATM kinase, PI3-K isoforms, and DNA-PK. Inhibits cell growth in cell lines w
SMLES:
CAS NO: 1481677-78-4
Standard In CHIKey: Insulin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H24N4O3S
M.Wt: 412.51
General Tips: for obtaining a higher concentration: Please warm the tube at 37℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/2/689
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in DMSO and to 10 mM in ethanol
Storage: Store at -20℃
Purity: >98%
Chemical Name: 4-[4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-1H-indole