Product Name: Afatinib (BIBW2992)
Subtitle: Irreversible EGFR/HER2 inhibitor
Biological Activity: Biological Activity of Afatinib (BIBW2992)Description Afatinib (BIBW2992) is an irreversible inhibitor of EGFR/HER2 for EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active aga
SMLES:
CAS NO: 1373423-53-0
Standard In CHIKey: Metabolic Disease inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H25ClFN5O3
M.Wt: 485.94
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/3/857
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility:
Storage:
Purity: >98%
Chemical Name: