Product Name: CTEP (RO4956371)
Subtitle: MGlu5 inhibitor
Biological Activity: Biological Activity of CTEP (RO4956371)Description CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM. Targets mGlu5 receptor IC50 2.2 nM
SMLES: CC1=C(N=C(N1C2=CC=C(C=C2)OC(F)(F)F)C)C#CC3=CC(=NC=C3)Cl
CAS NO: 66640-86-6
Standard In CHIKey: Neurokinin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H13ClF3N3O
M.Wt: 391.77
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/262/3/1203
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine