Product Name: CUDC-101
Subtitle: Multitargeted HDAC inhibitor
Biological Activity: Biological Activity of CUDC-101Description CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50 values of 4.4 nM, 2.4 nM, and 15.7 nM, respectively. Targets EGFR HDAC HDAC1 HDAC6 HDAC3 HDAC5 IC50 2.4 nM 4.4 nM 4.5 nM 5.1 nM
SMLES: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCCCCCC(=O)NO
CAS NO: 186692-46-6
Standard In CHIKey: TGF-beta) Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H26N4O4
M.Wt: 434.49
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/2/853
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide