Product Name: Costunolide
Subtitle: Apoptosis inducer
Biological Activity: Biological Activity of Costunolide Inhibitor of human telomerase activity (IC50 = 65 μM in MCF-7 breast cancer cells). Suppresses proliferation and induces apoptosis in a variety of human tumor cell lines. Selectively blocks endothelial cell proliferat
SMLES: CC1=C/CCC(=C/[C@H]2OC(=O)C(=C)[C@@H]2CC1)/C
CAS NO: 1219168-18-9
Standard In CHIKey: HRYLQFBHBWLLLL-AHNJNIBGSA-NKeap1-Nrf2 inhibitors
Standard InChI: InChI=1S/C15H20O2/c1-10-5-4-6-11(2)9-14-13(8-7-10)12(3)15(16)17-14/h5,9,13-14H,3-4,6-8H2,1-2H3/b10-5+,11-9+/t13-,14+/m0/s1
Typrof Compound: Sesquiterpenoids
Appearance: Powder
Formula: C15H20O2
M.Wt: 232.3
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/2/474
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in DMSO and to 50 mM in ethanol
Storage: Store at -20℃
Purity: ≥98%
Chemical Name: (3aS,6E,10E,11aR)-3a,4,5,8,9,11a-Hexahydro-6,10-dimethyl-3-methylene-cyclodeca[b]furan-2(3H)-one