Product Name: Daminozide
Subtitle: KDM2A inhibitor
Biological Activity: Biological Activity of DaminozideHistone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.55, 1.5 and 2.1 μM for PHF8, KDM2A and KDM7A respectively). Exhibits ≥ 60-fold selectivity for KDM2/7 demethylases over other histone demethylase
SMLES: CN(C)NC(=O)CCC(=O)O
CAS NO: 129497-78-5
Standard In CHIKey: NOQGZXFMHARMLW-UHFFFAOYSA-NPKA inhibitors
Standard InChI: InChI=1S/C6H12N2O3/c1-8(2)7-5(9)3-4-6(10)11/h3-4H2,1-2H3,(H,7,9)(H,10,11)
Typrof Compound:
Appearance:
Formula: C6H12N2O3
M.Wt: 160.17
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/2/706
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in water
Storage: Store at RT
Purity: >98%
Chemical Name: 1-(2,2-Dimethylhydrazide)butanedioic acid