Product Name: Floxuridine
Subtitle: Antineoplastic antimetabolite
Biological Activity: Biological Activity of FloxuridineAntineoplastic antimetabolite. Exhibits antiproliferative activity; inhibits thymidylate synthetase and disrupts DNA replication in human cells. Induces double-strand DNA breaks; activates ATR and ATM signaling pathways.
SMLES: c1c(c(nc(=O)n1[C@H]2C[C@@H]([C@H](O2)CO)O)O)F
CAS NO: 1638250-96-0
Standard In CHIKey: ODKNJVUHOIMIIZ-RRKCRQDMSA-Nc-Met_HGFR inhibitors
Standard InChI: InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
Typrof Compound:
Appearance:
Formula: C9H11FN2O5
M.Wt: 246.19
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/2/631
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 5-Fluoro-2-deoxyuridine