Product Name: Fludarabine
Subtitle: DNA synthsis inhibitor
Biological Activity: Biological Activity of FludarabinePurine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC50 = 1.54 μM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Inhibits
SMLES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(N=C2N)F
CAS NO: 473719-41-4
Standard In CHIKey: HBUBKKRHXORPQB-FJFJXFQQSA-NKinase_Inhibitor_Library inhibitors
Standard InChI: InChI=1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/m1/s1
Typrof Compound:
Appearance:
Formula: C10H12FN5O4
M.Wt: 285.23
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/3/1184
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: 9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine