Product Name: GSK-923295
Subtitle: CENP-E inhibitor,small-molecule
Biological Activity: Biological Activity of GSK-923295Description GSK-923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E) with Ki value of 3.2 nM. Targets CENP-E IC50 3.2 nM (Ki)
SMLES: CC(C)OC1=C(C=C(C=C1)C(=O)NC(CC2=CC=C(C=C2)C3=CN4C=CC=C(C4=N3)C(C)O)CNC(=O)CN(C)C)Cl
CAS NO: 1025015-40-0
Standard In CHIKey: Adenosine Deaminase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C32H38ClN5O4
M.Wt: 592.14
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/1
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 3-chloro-N-[(2S)-1-[[2-(dimethylamino)acetyl]amino]-3-[4-[8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl]phenyl]propan-2-yl]-4-propan-2-yloxybenzamide