Product Name: GW843682X
Subtitle: PLK1/PLK3 inhibitor,potent and selective
Biological Activity: Biological Activity of GW843682XSelective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively). Displays > 100-fold selectivity over ~30 other kinases tested including cdk1 and cdk2. Inhibit
SMLES: COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC
CAS NO: 1604810-83-4
Standard In CHIKey: Adenosine Kinase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H18F3N3O4S
M.Wt: 477.46
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/104
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 75 mM in DMSO and to 5 mM in ethanol
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide