Product Name: H-1152 dihydrochloride
Subtitle: Rho-kinase inhibitor
Biological Activity: Biological Activity of H-1152 dihydrochlorideRho-kinase (ROCK) inhibitor that displays high selectivity over other protein kinases (IC50 values are 0.012, 0.180, 0.360, 0.745, 3.03, 5.68 and 28.3 μM for ROCKII, CAMKII, PKG, Aurora A, PKA, PKC and MLCK
SMLES: CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)C.Cl.Cl
CAS NO: 1216941-48-8
Standard In CHIKey: Aldose Reductase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C16H23Cl2N3O2S
M.Wt: 392.34
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/117
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 50 mM in DMSO
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride