Product Name: Leflunomide
Subtitle: AHR agonist,immunosuppressive agent
Biological Activity: Biological Activity of LeflunomideInhibitor of dihydroorotate dehydrogenase (IC50 = 2.5 μM). Inhibits de novo pyrimidine synthesis in human T cells in vitro; also inhibits lymphocyte proliferation. Exhibits efficacy in several animal models of autoim
SMLES: Cc1c(cno1)C(=O)Nc2ccc(cc2)C(F)(F)F
CAS NO: 155148-31-5
Standard In CHIKey: VHOGYURTWQBHIL-UHFFFAOYSA-NFLT3 inhibitors
Standard InChI: InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)
Typrof Compound:
Appearance:
Formula: C12H9F3N2O2
M.Wt: 270.21
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/2/675
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in ethanol and to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: