Product Name: Letrozole
Subtitle: Non-steroidal aromatase inhibitor
Biological Activity: Biological Activity of LetrozolePotent, reversible non-steroidal aromatase inhibitor (IC50 = 11.5 nM). Displays antitumor effects in several animal models. Suppresses the endogenous aromatase-induced proliferation of MCF-7 cells.
SMLES: Cc1ccc(cc1)C(c2ccc(cc2)C)c3[nH]ncn3
CAS NO: 1798871-30-3
Standard In CHIKey: HPJKCIUCZWXJDR-UHFFFAOYSA-NAlkaloid inhibitors
Standard InChI: InChI=1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
Typrof Compound:
Appearance:
Formula: C17H11N5
M.Wt: 285.3
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/3/1370
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 4,4-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile