Product Name: Lomeguatrib
Subtitle: MGMT inhibitor
Biological Activity: Biological Activity of LomeguatribInhibitor of O6-methylguanine-DNA methyltransferase (MGMT); (IC50 = 0.009 μM in cell-free extracts from HeLa S3 cells); attenuates MGMT activity in vitro and in vivo. Enhances the antitumor activity of temozolomide i
SMLES: c1c(csc1COc2c3c(nc[nH]3)nc(n2)N)Br
CAS NO: 1375465-91-0
Standard In CHIKey: JUJPKFNFCWJBCX-UHFFFAOYSA-NPKC inhibitors
Standard InChI: InChI=1S/C10H8BrN5OS/c11-5-1-6(18-3-5)2-17-9-7-8(14-4-13-7)15-10(12)16-9/h1,3-4H,2H2,(H3,12,13,14,15,16)
Typrof Compound:
Appearance:
Formula: C10H8BrN5OS
M.Wt: 326.17
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/525
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 6-[(4-Bromo-2-thienyl)methoxy]-9H-purin-2-amine

Related Post