Product Name: MK-4827
Subtitle: PARP-1/-2 inhibitor,potent and selective
Biological Activity: Biological Activity of MK-4827MK-4827 is a potent, selective inhibitor of PARP 1 and PARP 2 with IC50 of 3.8 and 2.1 nM, respectively. Targets PARP1 PARP2 IC50 3.8 nM 2.1 nM
SMLES: C1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N
CAS NO: 1306760-87-1
Standard In CHIKey: EBI2_GPR183 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H20N4O
M.Wt: 320.39
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/646
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: DMSO
Storage:
Purity: >98%
Chemical Name: 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide