Product Name: MK-5108 (VX-689)
Subtitle: Aurora-A kinase inhibitor,highly selective
Biological Activity: Biological Activity of MK-5108 (VX-689)Description MK-5108 is a highly selective inhibitor of Aurora-A kinase with 0.064 nM. Targets Aurora-A IC50 0.064 nM
SMLES: C1CC(CCC1OC2=C(C(=CC=C2)Cl)F)(CC3=NC(=CC=C3)NC4=NC=CS4)C(=O)O
CAS NO: 176161-24-3
Standard In CHIKey: Opioid Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H21ClFN3O3S
M.Wt: 461.94
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/841
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid