Product Name: MLN8237 (Alisertib)
Subtitle: Aurora A Kinase inhibitor, Potent and selective
Biological Activity: Biological Activity of MLN8237 (Alisertib)Description Alisertib (MLN8237) is a selective inhibitor of Aurora A with IC50 of 1.2 nM. It has >200-fold higher selectivity for Aurora A than Aurora B. Targets Aurora A IC50 1.2 nM
SMLES: COC1=C(C(=CC=C1)F)C2=NCC3=CN=C(N=C3C4=C2C=C(C=C4)Cl)NC5=CC(=C(C=C5)C(=O)O)OC
CAS NO: 1431697-96-9
Standard In CHIKey: Leukotriene Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C27H20ClFN4O4
M.Wt: 518.92
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/778
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxybenzoic acid