Product Name: MPEP Hydrochloride
Subtitle: MGlu5 receptor antagonist
Biological Activity: Biological Activity of MPEP HydrochloridePotent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo
SMLES: CC1=CC=CC(=N1)C#CC2=CC=CC=C2.Cl
CAS NO: 129453-61-8
Standard In CHIKey: NEWKHUASLBMWRE-UHFFFAOYSA-NRAR_RXR inhibitors
Standard InChI: InChI=1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3
Typrof Compound:
Appearance:
Formula: C14H12ClN
M.Wt: 229.7
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/2/380
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 5 mM in water with gentle warming and to 100 mM in DMSO
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: 2-Methyl-6-(phenylethynyl)pyridine hydrochloride