Product Name: NPS-2143
Subtitle: CaSR antagonist
Biological Activity: Biological Activity of NPS-2143Description NPS-2143 is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM. Targets Ca(2+) receptor IC50 43 nM
SMLES: CC(C)(CC1=CC2=CC=CC=C2C=C1)NCC(COC3=C(C(=CC=C3)Cl)C#N)O
CAS NO: 55056-80-9
Standard In CHIKey: GPR119 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H25ClN2O2
M.Wt: 408.93
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/262/3/1103
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile