Product Name: PCI-24781 (CRA-024781)
Subtitle: Pan-HDAC inhibitor
Biological Activity: Biological Activity of PCI-24781 (CRA-024781)Description PCI-24781 is an inhibitor of HDACs with Ki values of 7 nM, 8.2 nM, 17 nM and 19 nM for HDAC1, HDAC3/SMRT, HDAC6 and HDAC2, respectively. Targets HDAC1 HDAC3/SMRT HDAC6 HDAC2 HDAC10 HDAC8
SMLES: CN(C)CC1=C(OC2=CC=CC=C21)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO
CAS NO: 1799753-84-6
Standard In CHIKey: Aromatase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H23N3O5
M.Wt: 397.42
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/2/880
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 3-[(dimethylamino)methyl]-N-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide