Product Name: PHA-680632
Subtitle: Aurora kinase inhibitor,novel and potent
Biological Activity: Biological Activity of PHA-680632Description PHA-680632 is a potent inhibitor of Aurora kinase with IC50 values of 27 nM, 135 nM and 120 nM for Aurora A, Aurora B and Aurora C, respectively. Targets Aurora A Aurora B Aurora C IC50 27
SMLES: CCC1=C(C(=CC=C1)CC)NC(=O)N2CC3=C(C2)NN=C3NC(=O)C4=CC=C(C=C4)N5CCN(CC5)C
CAS NO: 1211441-98-3
Standard In CHIKey: Oxytocin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C28H35N7O2
M.Wt: 501.62
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/851
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: N-(2,6-diethylphenyl)-3-[[4-(4-methylpiperazin-1-yl)benzoyl]amino]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazole-5-carboxamide