Product Name: Palbociclib (PD0332991) Isethionate
Subtitle: CDK4/6 inhibitor,highly selective
Biological Activity: Biological Activity of Palbociclib (PD0332991) IsethionateDescription Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM. Targets CDK4 CDK6 IC50 11 nM 16 nM
SMLES: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.C(CS(=O)(=O)O)O
CAS NO: 747412-49-3
Standard In CHIKey: Indoleamine 23-Dioxygenase IDO) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H29N7O2.C2H6O4S
M.Wt: 573.66
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/300
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Limited solubility
Storage:
Purity: >98%
Chemical Name: 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one;2-hydroxyethanesulfonic acid