Product Name: Rigosertib (ON-01910,Estybon)
Subtitle: Plk1 inhibitor
Biological Activity: Biological Activity of Rigosertib (ON-01910,Estybon)Description Rigosertib is a non-ATP-competitive small-molecule inhibitor of Plk1 with IC50 value of 9 nM. Targets Plk1 IC50 9 nM
SMLES: COc1ccc(cc1NCC(=O)[O-])CS(=O)(=O)C=Cc2c(cc(cc2OC)OC)OC.[Na+]
CAS NO: 1393466-87-9
Standard In CHIKey: Chloride Channel inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H24NNaO8S
M.Wt: 473.47
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/3/803
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: Sodium {[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]amino}acetate