Product Name: Ro 3306
Subtitle: An ATP-competitive, potent CDK1 inhibitor
Biological Activity: Biological Activity of Ro 3306ATP-competitive, potent cyclin-dependent kinase (cdk) 1 inhibitor (Ki values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A respectively). Induces G2/M phase cell cycle arrest and apoptosis. Downregulates the expressi
SMLES: O=C1N=C(NCC2=CC=CS2)S/C1=CC3=CC=C(N=CC=C4)C4=C3
CAS NO: 1849590-01-7
Standard In CHIKey: Stearoyl-CoA Desaturase SCD) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C18H13N3OS2
M.Wt: 351.45
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/442
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone