Product Name: Rucaparib (AG-014699,PF-01367338)
Subtitle: Potent PARP inhibitor
Biological Activity: Biological Activity of Rucaparib (AG-014699,PF-01367338)Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP1 with Ki of 1.4 nM. Targets PARP IC50 1.4 nM (Ki)
SMLES: OP(O)(O)=O.FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1
CAS NO: 566939-85-3
Standard In CHIKey: Salt-inducible Kinase SIK) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H18FN3O.H3PO4
M.Wt: 421.36
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/3/1103
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 8-fluoro-2-(4-((methylamino)methyl)phenyl)-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one phosphate